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Oral Manifestations in HIV/AIDS-Infected Children
Charles Mugisha Rwenyonyi1, Annet Kutesa, Louis Muwazi
1Department of Dentistry, School of Health Sciences, College of Health Sciences, Makerere University, Kampala, Uganda.
Insights
Most children with HIV/AIDS had oral lesions, especially those not on highly active antiretroviral therapy (HAART). Oral health in these children requires attention to improve their quality of life.
Area of Science:
- Oral health
- Pediatric infectious diseases
- HIV/AIDS management
Background:
- Oral manifestations are common in children with HIV/AIDS.
- Understanding these manifestations is crucial for comprehensive care.
Purpose of the Study:
- To identify factors affecting oral lesions in HIV/AIDS-infected children.
- To assess the prevalence and types of oral manifestations.
Main Methods:
- Cross-sectional study of 237 children (1-12 years) in Kampala.
- Interviews with guardians for demographic, hygiene, and medication data.
- Clinical examination for oral lesions using WHO criteria.
Main Results:
- 73% of children had at least one oral lesion; 19% experienced discomfort.
- Common lesions: cervical lymphadenopathy (60.8%), oral candidiasis (28.3%), gingivitis (19.0%).
- Lesions were less frequent in children on highly active antiretroviral therapy (HAART), except for dental caries (42.2% deciduous, 11.0% permanent).
Conclusions:
- A majority of HIV/AIDS-infected children present with oral lesions.
- Lesions are more prevalent in children not receiving HAART.
- Oral health interventions are essential for managing discomfort and improving well-being.
Objectives:
To assess factors influencing the distribution of oral manifestations in HIV/AIDS-infected children attending the Paediatric Infectious Disease Clinic in Mulago Hospital, Kampala.
Methods:
This was a cross-sectional study comprising 237 children (males/females: 113/124) aged 1 to 12 years. The parents/guardians were interviewed to obtain demographic information, oral hygiene practices, dietary habits and health seeking behaviours as well as any medications taken. The children were clinically examined for oral lesions based on World Health Organization criteria with modifications.
Results:
About 71.7% of the children cleaned their teeth. About 16.9% of the children had visited a dentist since birth, mainly for emergency care. One or more oral lesions were recorded in 73% of the children of whom 19.0% experienced discomfort during oral functions. Cervical lymphadenopathy, oral candidiasis and gingivitis were the most common soft tissue oral lesions: 60.8%, 28.3% and 19.0%, respectively. Except for dental caries, the overall frequency distribution of soft tissue oral lesions was significantly lower in children on highly active antiretroviral therapy (HAART) as compared to their counterparts not on HAART. The prevalence of dental caries in deciduous and permanent dentitions was 42.2% and 11.0%, respectively. Tooth brushing and previous visits to the dentist were indirectly and significantly associated with dental caries. About 5.9% (n=14) of the children had <200 CD3 + CD4 T-lymphocyte cells per μl of blood.
Conclusions:
The majority of the children had one or more oral lesions, particularly in the group not on HAART. Some of the lesions were associated with discomfort during oral functions.
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