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Are joint structure and function related to medial knee OA pain? A pilot study
Rebecca Avrin Zifchock1, Yatin Kirane, Howard Hillstrom
1Leon Root, MD Motion Analysis Laboratory, Department of Rehabilitation, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.
Measures of knee structure and function, specifically medial joint space and peak adduction angle, effectively predict knee osteoarthritis pain. Targeting these variables may improve pain relief for patients.
Area of Science:
- Orthopedics
- Biomechanics
- Rheumatology
Background:
- Knee osteoarthritis (OA) severity is typically assessed using joint structure, function, and pain measures.
- The interrelationships between these diverse OA assessment measures remain unclear.
Purpose of the Study:
- To examine relationships between knee structure (range of motion, tibiofemoral angle, medial joint space), function (KOOS, adduction angle/moment), and pain (VAS).
- To identify key variables that predict knee pain in medial knee OA patients.
Main Methods:
- 15 medial knee OA patients underwent VAS pain assessment, KOOS questionnaire, 3-D gait analysis, and radiographic examination.
- Pearson correlation assessed parameter relationships; stepwise multiple regression identified pain predictors.
Main Results:
- Subjective and most objective measures correlated, except adduction moment.
- Medial joint space and peak adduction angle were the strongest predictors of knee pain (r(2) = 0.73).
- All variables, except peak adduction moment, correlated with VAS knee pain.
Conclusions:
- Medial joint space and peak adduction angle are valuable predictors of knee pain in medial knee OA.
- Therapeutic interventions targeting these structural and functional parameters may enhance pain relief.
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