Related Experiment Video
Updated: May 30, 2026

09:32
Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model
Published on: February 23, 2020
Morphological state as a predictor for reintervention and mortality after EVAR for AAA.
Tomas Ohrlander1, Magnus Dencker, Stefan Acosta
1Eksjö County Hospital, Malmö, Sweden.
Cardiovascular and Interventional Radiology
|July 20, 2011
Summary
Aorto-iliac morphology significantly impacts outcomes after endovascular aneurysm repair (EVAR) for abdominal aortic aneurysms (AAA). Specific iliac artery characteristics and anemia predict reinterventions and long-term mortality.
Area of Science:
- Vascular Surgery
- Medical Imaging
- Biomedical Engineering
Background:
- Endovascular aneurysm repair (EVAR) is a common treatment for infrarenal abdominal aortic aneurysms (AAA).
- Patient-specific anatomical factors may influence the long-term success of EVAR.
- Understanding these factors is crucial for improving patient outcomes and reducing reintervention rates.
Purpose of the Study:
- To evaluate the association between aorto-iliac morphological characteristics and the need for reintervention in patients undergoing standard EVAR for AAA.
- To identify morphological predictors of all-cause long-term mortality in this patient cohort.
Main Methods:
- Prospective enrollment of 304 patients treated with EVAR (Zenith Stentgrafts) between May 1998 and February 2006.
- Data collection included comorbidities and preoperative aneurysm morphology.
- Follow-up extended to December 1, 2010, with a median of 68 months, monitoring reinterventions and mortality.
Main Results:
- A greater common iliac artery diameter was an independent predictor of increased reinterventions (HR 1.037).
- Severe angulation of the iliac arteries (HR 1.018) and anemia (HR 2.79) were independently associated with all-cause long-term mortality.
- The 5-year reintervention-free survival rate was 51.6%.
Conclusions:
- Preoperative aorto-iliac morphology is a significant factor influencing reintervention rates after EVAR for AAA.
- Morphological characteristics and patient comorbidities like anemia are linked to long-term mortality following EVAR.
- These findings highlight the importance of detailed anatomical assessment in EVAR planning.
Related Concept Videos
Aneurysm III: Interprofessional Care
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Aortic Regurgitation III: Medical Management
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
Aortic Regurgitation I: Introduction
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...