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Hot on the trail of trehalose: a carbohydrate-based method for imaging Mycobacterium tuberculosis

Dennis C Koester1, Shahid I Awan, Daniel B Werz

  • 1Institut für Organische und Biomolekulare Chemie, Georg-August Universität Göttingen, Tammannstrasse 2, 37077 Göttingen, Germany.

Chembiochem : a European Journal of Chemical Biology
|July 20, 2011
PubMed
Abstract

No abstract available in PubMed .

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Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...

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