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Updated: May 30, 2026

11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Proteinuria with fumaric acid ester treatment for psoriasis
S Ogilvie1, S Lewis Jones, R Dawe
1Department of Dermatology, Ninewells Hospital, Dundee, UK.
Clinical and Experimental Dermatology
|July 21, 2011
Summary
Fumaric acid esters (FAE) are generally safe for psoriasis, but can cause reversible proteinuria. This finding supports the use of dimethylfumaric (DMF) ester for psoriasis treatment.
Area of Science:
- Dermatology
- Nephrology
- Pharmacology
Background:
- Fumaric acid esters (FAE) are established systemic treatments for psoriasis, generally considered safe.
- Adverse effects typically include gastrointestinal issues, lymphopenia, and flushing; renal toxicity is rare.
- Previous studies indicated a low incidence of renal issues with FAE in psoriasis patients.
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