Regional cortical thickness and cognitive functions in non-demented Parkinson's disease patients: a pilot study
C Pellicano1, F Assogna, F Piras
1Movement Disorder Unit, Sant'Andrea Hospital, Rome, Italy.
European Journal of Neurology
|July 21, 2011
Abstract
Background And Purpose:
The pathology of neuropsychological deficits in Parkinson's disease (PD) is incompletely defined.
Methods:
We investigated cortical thickness and neuropsychological performances in non-demented patients with PD and healthy controls.
Results:
Patients showed significant cortical thinning in right middle temporal and left fusiform cortices. Verbal memory performance was related with left fusiform thinning.
Conclusions:
Cognitive and cortical changes in non-demented patients with PD are detectable and clearly related.
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