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Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Typing01:10

Blood Typing

Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...
Characteristics and Functions of Blood01:26

Characteristics and Functions of Blood

Blood is specialized connective tissue comprising about 8% of the body mass. It has a thick, liquid extracellular matrix that contains cells, dissolved proteins, and electrolytes, making it five times more viscous than water. Blood is warm, around 38°C, and has an alkaline pH ranging from 7.35 to 7.45.
The primary function of blood is to transport oxygen and carbon dioxide between tissues and the lungs. Oxygenated blood is bright red, while oxygen-depleted blood is darker. It also carries...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Composition of Blood01:22

Composition of Blood

The blood in our bodies comprises three major components: blood plasma, formed elements, and the extracellular matrix. Blood plasma is a yellowish fluid that constitutes 55% of the total blood volume. It is primarily made up of water and essential substances such as electrolytes and proteins. Blood plasma serves as a medium for transporting blood cells and also contains nutrients, enzymes, hormones, antibodies, and gases.
Formed elements constitute the remaining 45% of the blood volume. These...

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Related Experiment Video

Updated: May 30, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Blood component therapy: Which, when and how much.

Rajesh Chand Arya1, Gs Wander, Pankaj Gupta

  • 1Department of Cardiac Anesthesiology, Hero DMC Heart Institute, Ludhiana.

Journal of Anaesthesiology, Clinical Pharmacology
|July 21, 2011
PubMed
Summary
This summary is machine-generated.

Blood transfusion involves administering blood products during surgery. Proper use of blood components is crucial due to risks and costs, with this review detailing common components and new therapies.

Keywords:
Blood transfusionbleeding disorderblood componentscoagulopathy

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Isolation and Cryopreservation of Highly Viable Human Peripheral Blood Mononuclear Cells From Whole Blood: A Guide for Beginners
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Isolation and Cryopreservation of Highly Viable Human Peripheral Blood Mononuclear Cells From Whole Blood: A Guide for Beginners

Published on: October 25, 2024

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Last Updated: May 30, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Isolation and Cryopreservation of Highly Viable Human Peripheral Blood Mononuclear Cells From Whole Blood: A Guide for Beginners
10:48

Isolation and Cryopreservation of Highly Viable Human Peripheral Blood Mononuclear Cells From Whole Blood: A Guide for Beginners

Published on: October 25, 2024

Area of Science:

  • Anesthesiology and Perioperative Medicine
  • Hematology
  • Transfusion Medicine

Background:

  • Blood transfusion is a critical perioperative intervention.
  • Blood component therapy has recognized significance in managing various medical conditions.
  • Potential adverse effects and costs necessitate adherence to proper transfusion indications.

Purpose of the Study:

  • To discuss commonly used blood components.
  • To highlight new developments in blood component therapy.
  • To present evidence-based recommendations for transfusion practices.

Main Methods:

  • Review of current literature on blood component therapy.
  • Analysis of recommendations from academic and clinical studies.
  • Brief discussion of individual coagulation factors.

Main Results:

  • Overview of established and emerging blood components.
  • Summary of clinical guidelines for blood component use.
  • Insights into the application of specific coagulation factors.

Conclusions:

  • Optimizing blood component therapy requires understanding current components and advancements.
  • Adherence to evidence-based recommendations minimizes transfusion risks and costs.
  • Further research may refine indications and expand applications of blood products.