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Updated: May 30, 2026
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Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
Cerebral vasospasm following traumatic subarachnoid hemorrhage
Bahram Aminmansour1, Abbas Ghorbani, Davood Sharifi
1Department of Neurosurgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Summary
Cerebral vasospasm frequently occurs after traumatic subarachnoid hemorrhage (tSAH). Severe traumatic brain injury (TBI) increases the likelihood of developing vasospasm, a condition that can be prevented.
Area of Science:
- Neurosurgery
- Neurology
- Critical Care Medicine
Background:
- Cerebral vasospasm is a significant cause of mortality and morbidity following aneurysmal subarachnoid hemorrhage (SAH).
- Understanding vasospasm incidence after traumatic SAH is crucial for patient management.
- This study investigates vasospasm in traumatic SAH patients and its relation to injury severity.
Purpose of the Study:
- To determine the incidence of cerebral vasospasm in patients with traumatic subarachnoid hemorrhage (tSAH).
- To explore the association between cerebral vasospasm and the severity of traumatic brain injury (TBI).
Main Methods:
- A cross-sectional study involving head-injured patients with SAH confirmed by CT scan.
- Glasgow Coma Scale (GCS) assessed trauma severity; Transcranial Doppler ultrasonography evaluated vasospasm.
- Vasospasm criteria included specific mean flow velocities in the Middle Cerebral Artery (MCA), Anterior Cerebral Artery (ACA), and basilar artery.
Main Results:
- Out of 77 enrolled patients, 64 completed the study; 42.1% experienced vasospasm.
- Middle Cerebral Artery (MCA) vasospasm was most common (55.5%) in the first two weeks post-trauma.
- Incidence of vasospasm was higher in patients with severe TBI compared to moderate or mild TBI.
Conclusions:
- Traumatic subarachnoid hemorrhage (tSAH) is linked to a high rate of cerebral vasospasm.
- Severe traumatic brain injury (TBI) presents a higher risk for developing cerebral vasospasm.
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