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Fulminant pulmonary edema following intravenous administration of radiocontrast media
O Vandenplas1, P Hantson, A Dive
1Service de Soins Intensifs, Cliniques Universitaires, St-Luc, Bruxelles.
Acta Clinica Belgica
|January 1, 1990
Abstract:
A 29-year-old woman who developed fulminant pulmonary edema several minutes after intravenous administration of radiocontrast media (RCM) is reported. The low pulmonary-capillary wedge pressure and the high protein concentration in pulmonary edema fluid indicated a noncardiogenic pulmonary edema related to increased lung vascular permeability. Laboratory studies showed a slight decrease of several complement components (C3, C4 and factor B) and a transient consumption coagulopathy. Potential pathophysiologic mechanisms involved in RCM- induced pulmonary edema are discussed.