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Updated: May 30, 2026
06:52
Positron Emission Tomography Using 64-Copper as a Tracer for the Study of Copper-Related Disorders
Published on: April 28, 2023
A case of isolated elevated copper levels during pregnancy
Latoya R Walker1, Meghan Rattigan, Joseph Canterino
1Department of Obstetrics and Gynecology, Jersey Shore University Medical Center, 1945 Route 33, Neptune, NJ 07753, USA. Irwmd2b05@hotmail.com
Journal of Pregnancy
|July 21, 2011
Summary
Elevated copper levels in pregnancy are rare but can cause serious complications. Zinc therapy successfully normalized copper levels, resulting in a healthy infant and mother.
Area of Science:
- Obstetrics and Gynecology
- Metabolic Disorders
- Maternal-Fetal Medicine
Background:
- Abnormal copper metabolism is a rare condition outside of Wilson's Disease.
- Elevated copper levels during pregnancy are linked to intrauterine growth restriction, preeclampsia, and neurological issues.
Observation:
- A 32-year-old woman with a history of elevated copper levels in pregnancy and affected children presented for routine care.
- She opted for zinc therapy instead of chelation during this pregnancy.
- Her previous pregnancies were complicated by elevated copper levels, with her first child diagnosed with autism and experiencing myocardial infarctions.
Findings:
- The patient delivered a healthy infant with normal copper levels.
- Zinc therapy was chosen as an alternative to chelation during this pregnancy.
- Previous pregnancies were complicated by elevated maternal and infant copper levels.
Implications:
- Prompt diagnosis and management of copper metabolism alterations in pregnancy are crucial.
- Zinc therapy may be a viable alternative for managing elevated copper levels during pregnancy.
- Effective management can prevent adverse fetal and maternal outcomes, including growth restriction, neurological deficits, and preeclampsia.
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