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Polymer Microarrays for High Throughput Discovery of Biomaterials
Published on: January 25, 2012
Development of encoded particle-polymer arrays for the accelerated screening of antifouling layers
Darby Kozak1, Prakash Kithva, Jacinda Bax
1Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, Australia 4072. d.kozak@uq.edu.au
Chemical Communications (Cambridge, England)
|July 21, 2011
Abstract:
A multiplexed screening methodology for the rapid development of antifouling polymer surfaces is presented. An array of protein resistant polymer layers with high grafting (>100 mg m(-2)) were polymerized on optically encoded particles. Multiplexed analysis showed a 97% reduction in nonspecific protein adsorption for all polymer layers created.
