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Updated: May 30, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Prospective memory impairment in mild cognitive impairment: an analytical review
Alberto Costa1, Carlo Caltagirone, Giovanni Augusto Carlesimo
1I.R.C.C.S. Fondazione Santa Lucia, Via Ardeatina 306, 00179, Rome, Italy. a.costa@hsantalucia.it.
Abstract:
Mild cognitive impairment (MCI) is a heterogeneous condition characterized by the presence in an otherwise healthy elderly individual of cognitive deficits involving specific domains in the absence of significant functional impairments. Reports indicate that prospective memory (PM), that is, the ability to remember to execute delayed intentions, is impaired in individuals with MCI. The present review discusses the current debate in the literature on PM functioning in MCI by focusing on the relationship between prospective retrieval and retrospective memory functioning. Analysis of the reported evidence revealed that both the prospective component and the retrospective component of PM can be impaired in MCI. Declarative memory dysfunction may account for the retrospective memory impairment, while either reduced executive abilities or a deficit of reflexive mechanisms could explain the prospective component impairment.
Insights
Prospective memory (PM) is often impaired in mild cognitive impairment (MCI). Both the ability to remember future intentions and recall past information can be affected in individuals with MCI.
Area of Science:
- Neuroscience
- Gerontology
- Cognitive Psychology
Background:
- Mild cognitive impairment (MCI) affects elderly individuals with cognitive deficits but without significant functional impairment.
- Prospective memory (PM), the ability to recall future intentions, is frequently impaired in MCI.
- Understanding PM deficits is crucial for diagnosing and managing MCI.
Purpose of the Study:
- To review the current literature on prospective memory (PM) functioning in mild cognitive impairment (MCI).
- To examine the relationship between prospective retrieval and retrospective memory in MCI.
- To identify potential underlying mechanisms for PM impairment in MCI.
Main Methods:
- Literature review of studies investigating prospective memory in mild cognitive impairment (MCI).
- Analysis of the prospective and retrospective components of PM.
- Examination of the relationship between memory domains and executive functions.
Main Results:
- Evidence suggests both prospective and retrospective memory components of PM are impaired in MCI.
- Declarative memory dysfunction may underlie retrospective memory deficits in MCI.
- Reduced executive functions or reflexive mechanism deficits may explain prospective component impairment in MCI.
Conclusions:
- PM deficits in MCI are complex, involving both future intention recall and past information retrieval.
- Impaired declarative memory and executive functions contribute to PM difficulties in MCI.
- Further research is needed to elucidate the specific neural and cognitive mechanisms of PM impairment in MCI.
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