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Updated: May 30, 2026

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats
Published on: September 19, 2025
Motion correction using coil arrays (MOCCA) for free-breathing cardiac cine MRI
Peng Hu1, Susie Hong, Mehdi H Moghari
1Division of Cardiovascular, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA.
None:
In this study, we present a motion correction technique using coil arrays (MOCCA) and evaluate its application in free-breathing respiratory self-gated cine MRI. Motion correction technique using coil arrays takes advantages of the fact that motion-induced changes in k-space signal are modulated by individual coil sensitivity profiles. In the proposed implementation of motion correction technique using coil arrays self-gating for free-breathing cine MRI, the k-space center line is acquired at the beginning of each k-space segment for each cardiac cycle with 4 repetitions. For each k-space segment, the k-space center line acquired immediately before was used to select one of the 4 acquired repetitions to be included in the final self-gated cine image by calculating the cross correlation between the k-space center line with a reference line. The proposed method was tested on a cohort of healthy adult subjects for subjective image quality and objective blood-myocardium border sharpness. The method was also tested on a cohort of patients to compare the left and right ventricular volumes and ejection fraction measurements with that of standard breath-hold cine MRI. Our data indicate that the proposed motion correction technique using coil arrays method provides significantly improved image quality and sharpness compared with free-breathing cine without respiratory self-gating and provides similar volume measurements compared with breath-hold cine MRI.
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