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Asymmetrical Flow Field-Flow Fractionation for Sizing of Gold Nanoparticles in Suspension

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Nanoparticle characterization by cyclical electrical field-flow fractionation.

Julien Gigault¹, Bruce K Gale, Isabelle Le Hecho

¹Université de Pau et des Pays de l'Adour (UPPA)/CNRS Laboratoire de Chimie analytique Bio-Inorganique et Environnement, UMR IPREM 5254-Technopôle Hélioparc, Av. du Président Angot, 64053 Pau Cedex, France.

Analytical Chemistry

|July 22, 2011

Summary

This summary is machine-generated.

Cyclical electrical field flow fractionation (CyElFFF) effectively characterizes nanomaterials and colloidal particles. Optimized conditions enable reliable separation and analysis based on electrophoretic mobility.

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Area of Science:

Analytical Chemistry
Materials Science
Nanotechnology

Background:

Characterization of nanomaterials and colloidal particles is crucial for various scientific and industrial applications.
Cyclical electrical field flow fractionation (CyElFFF) offers a potential method for such analyses.

Purpose of the Study:

To experimentally demonstrate and optimize the analytical potential of CyElFFF for nanomaterial and colloidal particle characterization.
To investigate the influence of operating parameters on CyElFFF performance.

Main Methods:

Experimental investigation of CyElFFF with varying operating parameters.
Analysis of retention mechanisms and fractionation power.
Comparison of theoretical and experimental behavior for nanoparticles.

Main Results:

Voltage and frequency of the oscillating electrical field significantly control the separation mode.
Mobile phase flow rate is critical for fractionation efficiency.
Defined operating conditions allow reliable CyElFFF analysis of diverse nanoparticles.

Conclusions:

Optimized CyElFFF is a powerful tool for nanoparticle separation and characterization.
The technique is based on electrophoretic mobility.
Demonstrated reliable analytical potential for nanomaterials and colloidal particles.