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Updated: May 30, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Bent dinuclear platinum(II) halo-bridged carbonyl complexes
Daniela Belli Dell'Amico1, Luca Labella, Fabio Marchetti
1Dipartimento di Chimica e Chimica Industriale, Università di Pisa, via Risorgimento 35, I-56126 Pisa, Italy. belli@dcci.unipi.it
Abstract:
Crystals of trans-Pt₂(μ-X)₂X₂(CO)₂ (X = Br, I) have been grown and their molecular and crystalline structures have been solved by X-ray diffraction methods. In both cases the dinuclear molecules are bent, with a bending angle of 164.6° and 156.5° for the bromide and the iodide, respectively. While the structure of the bromo-derivative is reported here for the first time, a modification of trans-Pt₂(μ-I)₂I₂(CO)₂ with planar centrosymmetric molecules is known. This appears to be a rare case of a platinum(II) halo-bridged derivative structurally characterized in both bent and planar forms.
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