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Relationship between medication use and cardiovascular disease health outcomes in the Jackson Heart Study
Clifton C Addison1, Brenda W Jenkins, Daniel Sarpong
1Jackson Heart Study/Project Health, Jackson State University, 350 W. Woodrow Wilson Drive, Suite 701, Jackson, MS 39213, USA. clifton.addison@jsums.edu
Insights
Many African Americans do not adhere to prescribed cardiovascular disease (CVD) medications due to various reasons, including side effects and forgetfulness. Improving communication with healthcare providers can enhance medication adherence and health outcomes.
Area of Science:
- Cardiovascular Health
- Public Health
- Medical Adherence
Background:
- Cardiovascular disease (CVD) remains a significant health concern, particularly within the African American population.
- Non-adherence to prescribed medications is a widespread issue negatively impacting treatment efficacy for conditions like atherosclerosis.
- Despite available treatments, many at-risk individuals do not benefit due to poor adherence to medical advice.
Purpose of the Study:
- To investigate the association between demographic factors, behavioral patterns (including medication adherence), and health outcomes in African Americans.
- To identify common reasons for non-adherence to cardiovascular medications in this population.
- To inform strategies for improving medication compliance and health outcomes.
Main Methods:
- Utilized data from standardized interviews of 5301 African Americans in the Jackson Heart Study.
- Collected data on medication use (blood pressure, cholesterol, diabetes, blood thinners) and reasons for non-adherence.
- Analyzed demographic parameters, behavioral factors, and health outcomes.
Main Results:
- Nearly 52% reported taking blood pressure medication, 14% cholesterol, 16% diabetes, and 19% blood-thinning medication.
- Primary reasons for non-adherence included being busy/forgetful (47%), attempting to manage without medication (23%), cost (18%), side effects (19%), and functional impairment (17%).
- Unacceptable secondary effects were a significant driver of non-compliance.
Conclusions:
- The African American population can benefit from increased awareness of CVD risk factors and treatment benefits.
- Addressing medication side effects through open communication with healthcare providers is crucial for improving adherence.
- Enhanced patient-provider communication can lead to better-tolerated regimens, increased compliance, and improved cardiovascular health outcomes.
Abstract:
Even though some medications have the potential to slow the progress of atherosclerosis and development of CVD, there are many at-risk individuals who continue to resist the benefits that are available by not following the advice of medical professionals. Non-adherence to prescribed drug regimens is a pervasive medical problem that negatively affects treatment outcomes. Information from standardized interviews of 5301 African Americans participating in the Jackson Heart Study was examined to determine the association between demographic parameters, behavior including adherence to prescribed medical regimens, and health outcomes. Data were also collected at Annual Follow-Up and Surveillance visits. During the two weeks prior to the examination visit, almost 52% of the participants reported taking blood pressure medication, 14% took cholesterol medication, 16% took medication for diabetes, and 19% took blood thinning medication. Of those who did not take the prescribed medications, the reasons given were the following: 47% were in a hurry, too busy, or forgot to take medications; 23% were trying to do without medications; 18% had no money to purchase medications; 19% indicated that the medications made them feel bad; 17% felt that they could not carry out daily functions when taking medications. The African American population can benefit from heightened awareness of the risk factors that are associated with CVD and the benefits of following a prescribed treatment regimen. Unacceptable secondary effects of prescribed medication comprised an important cause of non-compliance. Encouragement of this population to communicate with their healthcare providers to ensure that medication regimens are better tolerated could increase compliance and improve health outcomes.
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