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Updated: May 30, 2026

Applications of pHluorin for Quantitative, Kinetic and High-throughput Analysis of Endocytosis in Budding Yeast
Published on: October 23, 2016
Rab GTPases and tethering in the yeast endocytic pathway
Jens Lachmann1, Christian Ungermann, Siegfried Engelbrecht-Vandré
1Department of Biology/Chemistry; Biochemistry Section; University of Osnabrück; Osnabrück, Germany.
Abstract:
Within eukaryotic cells, Rab GTPases control the maturation of early to late endosomes and their subsequent fusion with the vacuole. Within this ExtraView, we will focus on our recent findings regarding the activation of the Rab7 homolog Ypt7 in yeast and its interplay with the two multisubunit tethering complexes CORVET and HOPS.
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