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Updated: May 30, 2026

Fast and Specific Assessment of the Halogenating Peroxidase Activity in Leukocyte-enriched Blood Samples
Published on: July 28, 2016
Myeloprolipherative disorder type chronic myeloid leukemia--eosinophilic form
Aida Arnautovic-Custovic1, Samira Hasic, Emina Kopic
1Clinic for Oncology, Hematology and Radiotherapy, Department of Hematology, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina' Policlinic for Blood Transfusion, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina. aidahem@yahoo.com
Abstract:
Chronic eosinophilic leukemia (CEL) is a very rare form of leucemia in the western world. Adequate response is seldomly achieved after treatment with corticosteroids, interferon-alfa (INF-alfa) and medications containing hydroxi-urea (Litalir). The study presents a patient with CEL with no initial therapeutic response to the use of corticosteroids, INF-alfa and hydroxy-urea, and with neither clinical nor hematological response. After setting a diagnosis of CEL, patient was ordinated Imatinib (Glivec tabbletes) in a daily dose of 200 mg. Two days afterwards there was an evident withdrawal of subjective and clinical symptoms of disease, and the complete blood count showed significant amendment.
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