Related Experiment Video
Updated: May 30, 2026

Manganese Oxide Nanoparticle Synthesis by Thermal Decomposition of Manganese(II) Acetylacetonate
Published on: June 18, 2020
Structural and spectroscopic characterization of metastable thiolate-ligated manganese(III)-alkylperoxo species
Michael K Coggins1, Julie A Kovacs
1Department of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Abstract:
Metastable Mn-peroxo species are proposed to form as key intermediates in biological oxidation reactions involving O(2) and C-H bond activation. The majority of these have yet to be spectroscopically characterized, and their inherent instability, in most cases, precludes structural characterization. Cysteinate-ligated metal-peroxos have been shown to form as reactive intermediates in both heme and nonheme iron enzymes. Herein we report the only examples of isolable Mn(III)-alkylperoxo species, and the first two examples of structurally characterized synthetic thiolate-ligated metal-peroxos. Spectroscopic data, including electronic absorption and IR spectra, and ESI mass spectra for (16)O vs (18)O-labeled metastable Mn(III)-OOR (R = (t)Bu, Cm) are discussed, as well as preliminary reactivity.
Related Concept Videos
Radical Oxidation of Allylic and Benzylic Alcohols
Oxidation of Alkenes: Syn Dihydroxylation with Potassium Permanganate
Structure and Nomenclature of Thiols and Sulfides
Preparation and Reactions of Thiols
Preparation and Reactions of Sulfides
Alkynes to Carboxylic Acids: Oxidative Cleavage

