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Updated: May 30, 2026

Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites
Published on: November 9, 2014
Effects of common dental materials used in preventive or operative dentistry on dentin permeability and
Salvatore Sauro1, Ian Thompson, Timothy F Watson
1Biomaterials, Biometrics & Biophotonics, King's College London Dental Institute, Guy's, King's College and St Thomas' Hospitals, London, United Kingdom.
Abstract:
The aim of this study was to evaluate the dentin remineralization induced by bioactive substances contained in common dental materials used in preventive and operative dentistry. Several materials were applied on human dentin segments. Dentin permeability was quantified using a fluid filtration system working at 20 cm H(2)O. Micro-Raman, SEM-EDX, and microhardness calculation were used to evaluate changes in the mineralization of dentin. Dentin treated with the prophylactic materials showed different dentin permeability values, in particular subsequent to immersion in remineralizing solutions (RSS). The bioactive glass (Sylc) was the only substance able to reduce dentin permeability after immersion in remineralizing solution and to show hydroxyapatite precipitation as a sign of dentin remineralization. The reduction in dentin permeability obtained after the application of the other prophylactic materials used in this study was due to the presence of the remnant material in the dentinal tubules, with no remineralization effect after storage in remineralizing solution. In conclusion, the results indicated that bioactive glass prophy powder may induce immediate remineralization of dentin.
