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Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders
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Noncardiac chest pain: diagnostic evaluation.

R Fass1, S R Achem

  • 1Section of Gastroenterology, Department of Medicine, Southern Arizona VA Health Care System, Tucson, Arizona 85723-0001, USA. ronnie.fass@va.gov

Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus
|July 23, 2011
PubMed
Summary

Noncardiac chest pain (NCCP) affects millions yearly, presenting a diagnostic challenge due to its similarity to cardiac pain. Gastroenterologists investigate esophageal causes using various tests after cardiac and pulmonary issues are ruled out.

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Area of Science:

  • Gastroenterology
  • Internal Medicine

Background:

  • Noncardiac chest pain (NCCP) is a prevalent and complex clinical issue affecting a significant portion of the population.
  • NCCP poses a diagnostic challenge as its symptoms often mimic cardiac pain, necessitating extensive evaluations.
  • Patients with excluded cardiac and pulmonary causes are frequently referred for gastrointestinal assessment, particularly for esophageal origins.

Purpose of the Study:

  • To outline the diagnostic dilemma presented by noncardiac chest pain.
  • To highlight the common referral pathway to gastroenterology for esophageal investigations.
  • To present the array of diagnostic tools available for identifying the source of NCCP.

Main Methods:

  • Review of diagnostic approaches for noncardiac chest pain.
  • Identification of common tests used in gastroenterology for chest pain evaluation.
  • Discussion of the differential diagnosis process for chest pain.

Main Results:

  • Noncardiac chest pain is a common condition with symptoms often indistinguishable from cardiac pain.
  • Exclusion of cardiac and pulmonary etiologies leads to gastroenterological referral for esophageal evaluation.
  • A range of diagnostic tests, including pH monitoring, motility studies, endoscopy, and therapeutic trials, are available.

Conclusions:

  • Noncardiac chest pain requires a systematic diagnostic approach, often involving gastroenterologists.
  • Esophageal sources are a primary focus in the differential diagnosis of NCCP after cardiac causes are excluded.
  • The availability of multiple diagnostic tests aids clinicians in determining the origin of noncardiac chest pain.