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Related Experiment Video

Updated: May 30, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
09:51

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

Decrease in high human chorionic gonadotropin in twin-twin transfusion syndrome following fetoscopic laser surgery.

Masachi Hanaoka1, Satoshi Hayashi, Mari Saito

  • 1Department of Maternal-Fetal and Neonatal Medicine, National Center for Child Health and Development, Okura, Setagaya-ku, Tokyo, Japan.

Fetal Diagnosis and Therapy
|July 23, 2011
PubMed
Summary
This summary is machine-generated.

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Maternal serum human chorionic gonadotropin (hCG) levels are closely linked to twin-twin transfusion syndrome (TTTS). Post-surgery hCG levels can indicate the effectiveness of fetoscopic laser surgery for TTTS.

Area of Science:

  • Perinatology
  • Maternal-fetal medicine
  • Reproductive endocrinology

Background:

  • Twin-twin transfusion syndrome (TTTS) is a serious complication of monochorionic twin pregnancies.
  • Maternal serum human chorionic gonadotropin (hCG) levels are known to be altered in TTTS.
  • Understanding the dynamics of hCG in TTTS is crucial for patient management.

Purpose of the Study:

  • To investigate maternal serum hCG concentrations in twin-twin transfusion syndrome (TTTS) before and after fetoscopic laser surgery.
  • To clarify the association between TTTS and hCG levels.
  • To evaluate hCG as a potential marker for treatment efficacy.

Main Methods:

  • Maternal serum hCG was measured in 120 TTTS patients pre-surgery and at 2 and 4 weeks post-surgery.

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Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
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Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye

Published on: September 5, 2011

Related Experiment Videos

Last Updated: May 30, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
09:51

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
09:52

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye

Published on: September 5, 2011

  • hCG levels were correlated with TTTS severity (Quintero stages).
  • Changes in hCG post-laser surgery were monitored.

    • Main Results:

    • Preoperative hCG levels were elevated (median 6.34 MoM).
    • Higher hCG concentrations were observed in advanced TTTS stages (III/IV) compared to earlier stages (I/II).
    • Effective laser surgery led to a significant decrease in hCG levels within 4 weeks, while recurrence was associated with persistent high hCG.

    Conclusions:

    • A strong association exists between maternal serum hCG levels and the status of TTTS.
    • Post-laser surgery changes in hCG concentration serve as a valuable indicator for assessing treatment effectiveness.
    • Monitoring hCG can aid in the early detection of TTTS recurrence.