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Updated: May 30, 2026

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A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
A piezoelectric motor-based microactuator-generated distractor for continuous jaw bone distraction.
Jong-Tae Park1, Jae-Gi Lee, Soo-Yeon Kim
1Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Center, Brain Korea 21 Project, Yonsei University College of Dentistry, Seoul, South Korea.
The Journal of Craniofacial Surgery
|July 23, 2011
Summary
This study introduces a novel microactuator-generated distractor (MAGD) for continuous jaw bone distraction, overcoming limitations of current devices. The MAGD system, utilizing a piezoelectric motor, is ready for small-animal models and promises reduced complications for future human applications.
Area of Science:
- Biomedical Engineering
- Oral and Maxillofacial Surgery
- Regenerative Medicine
Background:
- Distraction osteogenesis is a key technique for correcting maxillofacial deformities.
- Current continuous jaw bone distraction methods face challenges with device size and complexity, particularly using hydraulic or motor-driven plates.
- Miniaturization is crucial for effective distractor systems, but scaling results from animal models to clinical use remains difficult.
Purpose of the Study:
- To develop a novel microactuator-generated distractor (MAGD) system for continuous jaw bone distraction.
- To overcome the limitations of existing distraction devices, particularly regarding size and motor technology.
- To create a versatile system adaptable to various distraction protocols.
Main Methods:
- Development of a MAGD system incorporating a Squiggle piezoelectric motor and Windows-based control software.
- Implementation of software allowing simple selection of intermittent and continuous distraction protocols.
- Laboratory-scale testing to determine the device's maximum force output.
Main Results:
- The MAGD system was successfully developed, featuring a piezoelectric motor and user-friendly control software.
- The laboratory-scale MAGD demonstrated a maximum force of 3 N.
- The device is validated as ready for application in small-animal distraction models, including rats and mice.
Conclusions:
- The developed MAGD system offers a promising solution for continuous jaw bone distraction, addressing size and control limitations.
- Further refinement is necessary for human clinical application, but a fully implanted MAGD system is anticipated to minimize soft-tissue complications.
- The MAGD system has the potential to improve patient quality of life by supporting social activities and requiring minimal patient cooperation.

