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Updated: May 30, 2026

Surgical Correction for Pediatric Epiblepharon and Trichiasis
Published on: July 8, 2025
One-stage reconstruction technique for large congenital eyelid coloboma
Aiman Hashish1, Amr Mahmoud Awara
1Department of Ophthalmology, Tanta University, Tanta, Egypt.
Insights
Preputial skin grafts offer satisfactory cosmetic and functional results for reconstructing congenital eyelid colobomas in male infants. This innovative technique provides a viable alternative when traditional donor sites are unavailable.
Area of Science:
- Ophthalmology
- Plastic Surgery
- Pediatric Surgery
Background:
- Congenital eyelid coloboma presents significant functional and cosmetic challenges.
- Exposure keratopathy is a common complication in severe eyelid colobomas.
- Limited donor sites for skin grafts in infants necessitate alternative reconstructive strategies.
Purpose of the Study:
- To evaluate the functional and cosmetic outcomes of using preputial skin grafts for eyelid reconstruction in congenital coloboma.
- To assess the efficacy of a one-stage surgical repair technique.
Main Methods:
- A cohort of four male infants with large unilateral eyelid colobomas and exposure keratopathy underwent surgical repair.
- Reconstruction involved a sliding tarsoconjunctival flap combined with a free skin graft from the prepuce (post-circumcision).
- Surgical procedures were performed between March 2006 and August 2009 at Tanta University Eye Hospital, Egypt.
Main Results:
- All four patients achieved satisfactory cosmetic and functional outcomes with good color match using preputial skin grafts.
- The tarsoconjunctival sliding flap component yielded excellent functional and cosmetic results.
- Follow-up periods ranged from 7 to 36 months, demonstrating sustained positive outcomes.
Conclusions:
- Preputial skin grafts, in conjunction with tarsoconjunctival flaps, represent a highly effective method for reconstructing large eyelid defects in male infants.
- This technique is particularly valuable when conventional donor sites for skin grafts are inaccessible.
- The study supports the use of preputial skin as an adequate and aesthetically pleasing graft material for pediatric eyelid reconstruction.
Purpose:
To determine the functional and cosmetic outcome of using skin graft from prepuce (after circumcision) to reconstruct eyelids in congenital lid coloboma.
Patient & Methods:
Four male infants with large eyelid coloboma and marked exposure keratopathy were included. All the patients were selected from the outpatient clinic of Tanta University Eye Hospital, Egypt from March 2006 till August 2009. One-stage reconstruction was used to repair the defect. For upper eyelid coloboma, sliding tarsoconjunctival flap with a free skin graft from of skin of prepuce (after circumcision) was done.For lower lid coloboma, conjunctival dissection with reflection over the cornea with use of a free skin graft from prepuce.
Results:
All infants had large unilateral defect, 3 upper lids and 1 lower lid. The cosmetic and functional outcome of using skin of the prepuce was satisfactory with good color match in all cases. Also functional and cosmetic results of tarsoconjunctival sliding flap was excellent. All the cases were followed up for a period ranged from 7 to 36 months.
Conclusion:
Tarsoconjunctival rotational flap and the use of skin of prepuce are very helpful and seems to be an adequate method of reconstruction of large eyelid defect in male patients when the usual donor sites for skin grafts are not available as in infants.

