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Related Concept Videos

DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...

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Related Experiment Video

Updated: May 30, 2026

Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples
13:21

Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples

Published on: May 4, 2012

Microarray-based technology for glycomics analysis.

Jingqing Gao1, Lina Ma, Dianjun Liu

  • 1State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China.

Combinatorial Chemistry & High Throughput Screening
|July 26, 2011
PubMed
Summary
This summary is machine-generated.

Glycomics, the study of carbohydrates, is crucial in biology. Microarray techniques offer powerful tools for analyzing carbohydrate-protein interactions and cellular glycan profiles, advancing biological research.

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Printed Glycan Array: A Sensitive Technique for the Analysis of the Repertoire of Circulating Anti-carbohydrate Antibodies in Small Animals
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Microarray Polymer Profiling (MAPP) for High-Throughput Glycan Analysis
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Microarray Polymer Profiling (MAPP) for High-Throughput Glycan Analysis

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Last Updated: May 30, 2026

Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples
13:21

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Published on: May 4, 2012

Printed Glycan Array: A Sensitive Technique for the Analysis of the Repertoire of Circulating Anti-carbohydrate Antibodies in Small Animals
08:49

Printed Glycan Array: A Sensitive Technique for the Analysis of the Repertoire of Circulating Anti-carbohydrate Antibodies in Small Animals

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Microarray Polymer Profiling (MAPP) for High-Throughput Glycan Analysis
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Microarray Polymer Profiling (MAPP) for High-Throughput Glycan Analysis

Published on: September 29, 2023

Area of Science:

  • Glycomics and glycobiology
  • Carbohydrate-protein interactions
  • Molecular biology and biochemistry

Background:

  • Glycomics is vital in the post-genomic era due to the widespread biological roles of carbohydrate-protein interactions.
  • These interactions are implicated in fundamental cellular processes and pathogen infections.
  • Microarrays have emerged as effective tools for studying these interactions.

Purpose of the Study:

  • To review recent advancements in microarray-based techniques for glycomic studies.
  • To summarize the fabrication and application of glycan/lectin microarrays.
  • To discuss current challenges and bottlenecks in microarray glycomics.

Main Methods:

  • Review of existing literature on microarray development for glycomics.
  • Analysis of fabrication methods for glycan and lectin microarrays.
  • Evaluation of applications in carbohydrate-protein interaction studies and glycan profiling.

Main Results:

  • Microarray technologies have shown success in analyzing carbohydrate-protein interactions.
  • These techniques are valuable for profiling cell surface glycans.
  • Recent progress has been made in developing sophisticated microarray platforms.

Conclusions:

  • Microarray-based glycomics is a rapidly advancing field with significant potential.
  • Further development is needed to overcome existing fabrication and application challenges.
  • These techniques are essential for understanding biological processes and disease mechanisms.