Epinephrine autoinjector availability among children with food allergy
Related Experiment Video
Updated: May 30, 2026

Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
Karen A DeMuth1, Anne M Fitzpatrick
1Department of Pediatrics, Division of Pulmonary, Allergy, Cystic Fibrosis, and Sleep Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA. kdemuth@emory.edu
Insights
Many food-allergic children lack readily available epinephrine autoinjectors, increasing mortality risk. Training significantly improves autoinjector accessibility, highlighting the need for ongoing patient education on carrying epinephrine, especially during meals.
Area of Science:
- Allergy and Immunology
- Pediatric Emergency Medicine
- Public Health
Background:
- Anaphylaxis requires prompt epinephrine administration.
- Delayed epinephrine use is linked to fatal food allergy reactions.
- Availability of epinephrine autoinjectors in children with food allergies is a critical concern.
Purpose of the Study:
- To determine the availability rate of epinephrine autoinjectors in food-allergic children.
- To identify factors associated with epinephrine autoinjector carriage.
- To assess the impact of training on autoinjector accessibility.
Main Methods:
- Parents of food-allergic children completed questionnaires on allergy preparedness.
- Clinic staff recorded the immediate availability of epinephrine autoinjectors and medical alert bracelets.
- Data from 63 food-allergic children were analyzed.
Main Results:
- Only 59% of children had an epinephrine autoinjector present in the clinic.
- Epinephrine autoinjector training was associated with significantly increased odds of availability (aOR, 8.74).
- School-aged children (≥5 years) were less likely to have their autoinjector during meals and snacks compared to younger children.
Conclusions:
- A significant proportion of food-allergic children do not have their epinephrine autoinjectors readily accessible.
- Epinephrine autoinjector training is a key factor in improving autoinjector availability.
- Enhanced patient education is crucial to ensure epinephrine autoinjectors are accessible, particularly during eating occasions.
Abstract:
Epinephrine is the treatment of choice for anaphylaxis. Delay in administration of epinephrine is a known risk factor for food allergy reaction-related mortality; however, individuals with food allergy may not have epinephrine readily available. This study was designed to determine the percent of food-allergic children that have an epinephrine autoinjector readily available and factors associated with epinephrine autoinjector carriage rates. Parents completed a questionnaire on food allergy and food allergy preparedness. Staff recorded whether an epinephrine autoinjector and medical alert bracelet was immediately available in clinic. Parental responses from 63 food-allergic children were included. Fifty-nine percent (37/63) had an epinephrine autoinjector present in the clinic, and 79% (50/63) reported receiving training in epinephrine autoinjector use. There was no correlation between epinephrine autoinjector presence in the clinic and parental report of having an epinephrine autoinjector available at all times (phi = 0.21). Epinephrine autoinjector training was associated with increased odds of having an epinephrine autoinjector immediately available (adjusted odds ratio, 8.74 [1.69, 45.04]). Fewer school aged children (≥5 years old) reportedly had their epinephrine autoinjector with them when eating lunch (25% [8/32] versus 42% [13/31]; p = 0.002) or snacks (28% [9/32] versus 37% [13/31]; p = 0.005) when compared with those <5 years old. Many children do not have their epinephrine autoinjectors readily available despite parental report. Epinephrine autoinjector training improved the odds of having an epinephrine autoinjector readily available. Continued patient education on the importance of having an epinephrine autoinjector easily accessible, especially when eating, is important.
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