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Albuminuria: is it time to screen the general population?
Deidra C Crews1, L Ebony Boulware, Ron T Gansevoort
1Department of Medicine, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD, USA.
Advances in Chronic Kidney Disease
|July 26, 2011
Summary
Screening for albuminuria (a marker of kidney disease) can identify individuals at high risk for serious health problems like kidney failure and heart disease, guiding early intervention strategies.
Area of Science:
- Nephrology
- Public Health
- Preventive Medicine
Background:
- Albuminuria is linked to significant risks, including end-stage renal disease (ESRD), acute kidney injury (AKI), cardiovascular disease (CVD), and mortality.
- Clinicians propose population-based screening for albuminuria to identify high-risk individuals for early intervention.
Purpose of the Study:
- To review the literature on implementing albuminuria screening in the general population.
- To discuss key factors influencing screening protocols and suggest an approach for patient screening.
Main Methods:
- Literature review of studies addressing albuminuria screening.
- Analysis of factors including testing methods, albuminuria thresholds, test validity, follow-up frequency, and costs.
Main Results:
- Evidence supports albuminuria screening for risk stratification.
- Key considerations for implementation include test selection, threshold definition, and cost-effectiveness.
Conclusions:
- Albuminuria screening is a valuable tool for identifying individuals at elevated risk for adverse health outcomes.
- A structured approach to screening, considering various implementation factors, is recommended for clinical practice.
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