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Cevdet Uguz1, Inci Togan, Yildiz Eroglu

  • 1Department of Genetics, Faculty of Veterinary Medicine, Afyon Kocatepe University, A.N. Sezer Kampüsü, 03200 Afyon, Turkey; Biology Department, Middle East Technical University, 06531 Ankara, Turkey.

Environmental Toxicology and Pharmacology
|July 26, 2011
PubMed

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Like water, alcohols are weak acids and bases. This is attributed to the polarization of the O–H bond making the hydrogen partially positive. Moreover, the electron pairs on the oxygen atom of alcohol make it both basic and nucleophilic. Protonation of an alcohol converts hydroxide, a poor leaving group, into water—a good one. The two acid–base equilibria corresponding to ethanol are depicted below.