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A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis
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A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

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Risk factors associated with haemodynamic depression during and after carotid artery stenting

Xuegan Lian1, Min Lin, Shuanggen Zhu

  • 1Department of Neurology, Jinling Hospital, Second Military Medical University, 305 East Zhongshan Road, Nanjing 210002, China.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|July 26, 2011
PubMed

Insights

Severe calcified plaque, high-grade stenosis, bilateral stenting, and high balloon pressure during carotid artery stenting (CAS) increase the risk of hemodynamic depression (HD). These factors predict adverse outcomes in patients undergoing CAS.

Area of Science:

  • Cardiovascular Surgery
  • Interventional Cardiology
  • Neurosurgery

Background:

  • Carotid artery stenting (CAS) is a common procedure for treating carotid artery stenosis.
  • Hemodynamic depression (HD) is a potential complication during and after CAS.
  • Identifying risk factors for HD is crucial for patient management.

Purpose of the Study:

  • To investigate the risk factors associated with hemodynamic depression (HD) during and after carotid artery stenting (CAS).

Main Methods:

  • A cohort of 251 patients undergoing CAS were analyzed.
  • Patients were categorized into groups with and without HD based on predefined criteria.
  • Univariate analysis and logistic regression models were employed to identify risk factors.

Main Results:

  • Severe calcified plaque, stenosis >70%, and bilateral stenting were significantly associated with HD.
  • Balloon dilation pressure >8 atm was an independent risk factor for HD.
  • Other factors like lesion distance, dilation duration, and balloon size also showed associations.

Conclusions:

  • Patients with severe calcified plaque, >70% stenosis, bilateral stenting, and high balloon dilation pressure (>8 atm) are at higher risk of developing HD post-CAS.
  • These findings aid in risk stratification and peri-procedural management of CAS patients.

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