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Published on: March 22, 2012
Invasive aspergillosis arising from ureteral aspergilloma
Hoon Choi1, Il Sang Kang, Hun Soo Kim
1Department of Urology, Institute of Wonkwang Medical Science, Wonkwang University School of Medicine, Iksan, Korea.
Abstract:
Ureteral obstruction may develop in immunocompromised patients with an Aspergillus fungal infection. Infections can progress to invasive aspergillosis, which is highly lethal. We report a case of a 56-year-old man with alcoholic cirrhosis of the liver and diabetes. He had ureteral aspergilloma, discovered as a saprophytic whitish mass. It was treated by ureteroscopic removal, however, he refused antifungal treatment. His condition progressed to invasive aspergillosis, and died from sepsis and hepatorenal syndrome.
Insights
Invasive aspergillosis, a lethal fungal infection, can arise from ureteral obstruction in immunocompromised individuals. Despite initial treatment, a patient with cirrhosis and diabetes progressed to invasive disease and died from sepsis.
Area of Science:
- Mycology
- Infectious Diseases
- Nephrology
Background:
- Ureteral obstruction in immunocompromised patients can be caused by Aspergillus fungal infections.
- These infections may progress to invasive aspergillosis, a condition with high mortality.
- Patients with underlying conditions like liver cirrhosis and diabetes are at increased risk.
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