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The Establishment of a Murine Maxillary Orthodontic Model
Published on: October 27, 2023
Altered mandibular growth under functional posterior displacement in rats
Arcelino Farias-Neto1, Ana Paula Varela Brown Martins, Sidney Raimundo Figueroba
1Department of Prosthodontics and Periodontology, Piracicaba Dental School, State University of Campinas, Piracicaba, São Paulo, Brazil. saudeoral@yahoo.com.br
The Angle Orthodontist
|July 27, 2011
Summary
Posterior functional mandibular displacement in growing rats led to significantly shorter mandibular length. Ramus height and intercondylar distance showed no significant changes in this study.
Area of Science:
- Craniofacial development
- Orthodontics
- Animal models in research
Background:
- Functional mandibular displacement can impact craniofacial growth.
- Understanding these effects is crucial for orthodontic interventions.
Purpose of the Study:
- To investigate the effect of posterior functional mandibular displacement on mandibular growth in young rats.
- To test the hypothesis of no difference in mandibular growth between control and displaced groups.
Main Methods:
- Twenty female Wistar rats were divided into control and posterior displacement groups.
- Mandibular growth parameters were measured using cone-beam computed tomography after 8 weeks.
- Statistical analysis included ANOVA and t-tests.
Main Results:
- Mandibular length was significantly reduced in the posterior displacement group compared to controls (P < .0001).
- No significant differences were found in ramus height or intercondylar distance between groups.
Conclusions:
- Functional posterior mandibular displacement inhibits mandibular length growth in developing rats.
- This finding has implications for understanding the effects of malocclusion on skeletal development.
