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Musculoskeletal manifestations of hemophilia: imaging features

Sriram Jaganathan1, Shivanand Gamanagatti, Ankur Goyal

  • 1Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.

Current Problems in Diagnostic Radiology
|July 27, 2011
PubMed

The purpose of this pictorial assay is to demonstrate the imaging features of the various musculoskeletal manifestations of hemophilia, an X-linked disorder. Depending on the site of recurrent bleeding, musculoskeletal manifestation can be in the form of hemophilic arthropathy and/or soft tissue, intraosseous, or subperiosteal pseudotumors. Radiography, sonography, computed tomography, and especially magnetic resonance imaging help in the evaluation of hemophilic arthropathy and pseudotumors, providing accurate diagnosis, thus avoiding inadvertent procedures and related complications. Treatment includes replacement of clotting factors either continuously or when indicated, radionuclide or open synovectomy in cases of disabling arthropathy.

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