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Updated: May 30, 2026

Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes
Published on: December 16, 2019
Iron-catalyzed aryl- and alkenyllithiation of alkynes and its application to benzosilole synthesis
Eiji Shirakawa1, Seiji Masui, Rintaro Narui
1Department of Chemistry, Graduate School of Science, Kyoto University, Kyoto, 606-8502, Japan. shirakawa@kuchem.kyoto-u.ac.jp
Abstract:
Phenyl- and vinyllithiums having an alkyl substituent at their ortho- and cis-position, respectively, readily added to alkynes in the presence of 5 mol% of Fe(acac)(3). The reaction of o-(trimethylsilyl)phenyllithium with alkynes gave benzosiloles through an addition-cyclization sequence.
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