Related Experiment Video
Updated: May 30, 2026

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
[Gastric cancer: current status of multimodality treatment]
1Städtisches Klinikum Solingen, Klinik für Allgemein- und Viszeralchirurgie, Gotenstrasse 1, Solingen, Germany. meyer@klinikumsolingen.de
Background:
The overall prognosis of gastric cancer with an overall 5-year survival of 25% is still poor despite improvements of the surgical and perioperative procedures. To improve the surgical treatment results other therapeutic options as chemo- and/or radiotherapy have been investigated for more than 20 years.
Methods:
After a literature review, the results of actual trials of multimodality treatment were analysed and described.
Results:
Adjuvant treatment was less effective compared with neoadjuvant or perioperative chemotherapy performed in advanced tumour categories T3/4. Actual trials could show that the rate of curative (R0) resection can be augmented resulting in an increase of the overall 5-year survival rate of more than 10 %.
Conclusion:
To confirm this trend, further studies with high pathological and surgical quality control are necessary as well as a more exact definition of prediction and evaluation of the response following chemotherapy.
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