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Related Experiment Videos

Topical pharyngeal anesthesia for easing endoscopy: a double-blind, randomized, placebo-controlled study.

J Lachter1, R Jacobs, A Lavy

  • 1Department of Gastroenterology, Rambam Medical Center, Haifa, Israel.

Gastrointestinal Endoscopy
|January 1, 1990
PubMed
Summary
This summary is machine-generated.

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Cetacaine topical anesthetic spray showed no significant difference compared to placebo in reducing gagging during endoscopy. However, physicians noted easier endoscope insertion for first-time patients using Cetacaine.

Area of Science:

  • Anesthesiology
  • Gastroenterology

Background:

  • Topical anesthetics are used to reduce discomfort during endoscopic procedures.
  • Cetacaine is a commonly used topical anesthetic spray.

Purpose of the Study:

  • To evaluate the efficacy of Cetacaine topical anesthetic spray compared to a placebo.
  • To assess patient and physician perceptions of difficulty during endoscopy.

Main Methods:

  • A randomized, double-blind, placebo-controlled study involving 150 patients undergoing endoscopy.
  • Administration of Cetacaine or placebo spray prior to the procedure.
  • Patient and physician questionnaires to assess gagging, coughing, and ease of intubation.

Main Results:

  • No statistically significant differences were observed in patient-reported cough or gag reflex between Cetacaine and placebo groups.

Related Experiment Videos

  • Physicians reported significantly easier gastroscope insertion in first-time endoscopy patients pre-medicated with Cetacaine (p < 0.05).

    • Conclusions:

    • Cetacaine spray did not demonstrate a significant advantage over placebo in reducing gagging or coughing during endoscopy based on patient reports.
    • Physician-assessed ease of intubation was improved with Cetacaine in a specific subgroup (first-time patients).