[Intra-tubal gamete transfer: analysis of prognostic indices based on 62 treatment cycles]

Gamete intrafallopian transfer (GIFT) was applied in 55 couples in 62 treatment cycles. The overall pregnancy rate was 38.7% (24 of 62), the highest incidence of pregnancy being obtained in the group of tubal adhesions (8 [47%] of 17), in cases of multifactorial infertility (7 [44%] of 16) and of unexplained infertility (4 [36%] of 11). The multiple pregnancy rate was 21%, 17% ended in clinical abortions and one (4%) was a tubal pregnancy. Pregnancy was correlated with the number of oocytes transferred: whereas less than or equal to 3 oocytes were replaced in only 1 (4%) of 24 pregnant women, 9 (26%) of 34 non-pregnant women had less than or equal to 3 oocytes transferred (p less than 0.005). On comparing pregnant and non-pregnant women, no significant correlation was found for 1.) the degree of maturity of oocytes transferred, 2.) the percentage of supernumerary oocytes being successfully fertilized in vitro and 3.) the hormonal pattern observed during hyperstimulation with human menopausal gonadotropin.