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Alignment of distantly related protein structures: algorithm, bound and implications to homology modeling

Sheng Wang1, Jian Peng, Jinbo Xu

  • 1Toyota Technological Institute at Chicago, IL 60637, USA.

Bioinformatics (Oxford, England)
|July 28, 2011
PubMed
Abstract

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Protein domains are small structurally independent units that are part of a single amino acid chain.  Although these domains are often structurally independent, they may rely on synergistic effects to perform their functions as part of a larger protein. Protein domains may be conserved within the same organism, as well as across different organisms.
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