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Depression and outcomes in hospitalized Japanese patients with cardiovascular disease. - Prospective single-center

Tsuyoshi Suzuki1, Tsuyoshi Shiga, Kazue Kuwahara

  • 1Department of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.

Circulation Journal : Official Journal of the Japanese Circulation Society
|July 28, 2011
PubMed

Insights

Depression is common in Japanese cardiovascular patients and significantly increases their risk of adverse cardiovascular events and mortality. Early identification and management of depression are crucial for improving outcomes in this population.

Area of Science:

  • Cardiology
  • Psychiatry
  • Public Health

Background:

  • Depression is a known risk factor for cardiovascular disease (CVD).
  • Understanding depression prevalence and impact in CVD patients is vital for clinical practice.

Purpose of the Study:

  • To determine the prevalence of depression among Japanese inpatients with CVD.
  • To assess the association between depression and cardiovascular events or mortality.

Main Methods:

  • Prospective observational study of 505 Japanese CVD inpatients.
  • Depression screening using the Zung Self-Rating Depression Scale (SDS).
  • Primary outcome: time to death or cardiovascular event; Secondary outcome: death.

Main Results:

  • 22% of patients were diagnosed with depression (Zung SDS index score ≥ 60).
  • Depression was independently associated with higher rates of cardiovascular events and mortality (P<0.01).
  • Depression independently predicted adverse cardiovascular outcomes (HR, 2.25; 95% CI: 1.30-3.92).

Conclusions:

  • Depression is prevalent in Japanese CVD inpatients.
  • Depression is significantly linked to poorer cardiovascular outcomes, including mortality.
Abstract

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