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Obesity: an independent risk factor for insufficient hemostasis using the AngioSeal vascular closure device after

Peter Minko1, Marcus Katoh, Stefan Gräber

  • 1Department of Diagnostic and Interventional Radiology, University Hospital Saarland, Homburg/Saar, Germany. peterminko@yahoo.com

Cardiovascular and Interventional Radiology
|July 28, 2011
PubMed

Insights

Obesity is a risk factor for AngioSeal device failure in femoral artery closure. This vascular closure device had an 81% success rate, with kinks causing 8% of failures.

Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Medical Device Technology

Background:

  • Vascular closure devices (VCDs) are crucial for hemostasis after femoral artery access.
  • The AngioSeal device is a commonly used VCD for achieving rapid closure.
  • Understanding factors influencing VCD efficacy is vital for patient outcomes.

Purpose of the Study:

  • To evaluate the efficacy of the AngioSeal VCD following antegrade common femoral artery (CFA) puncture.
  • To identify patient-specific factors associated with AngioSeal device failure.

Main Methods:

  • A prospective study enrolled 120 patients undergoing lower limb vascular interventions with antegrade CFA access.
  • AngioSeal devices (6F or 8F) were used for hemostasis post-intervention.
  • Patient data including coagulation status, BMI, and groin characteristics were collected.

Main Results:

  • Hemostasis was achieved in 81% of patients; 10% required manual compression for bleeding.
  • Device-related failures occurred in 8% due to sheath kinking and 2% due to anchor dislodgement.
  • Unsuccessful sealing was significantly associated with higher Body Mass Index (BMI).

Conclusions:

  • Obesity (elevated BMI) is an independent risk factor for AngioSeal device failure.
  • Sheath kinking is a significant technical complication impacting hemostasis.
  • Optimizing VCD use requires consideration of patient BMI and potential device-related issues.
Abstract

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