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Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
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Published on: October 28, 2020

The prognostic value of early left ventricular longitudinal systolic dysfunction in asymptomatic subjects with

Giovanni Di Salvo1, Vitantonio Di Bello, Alessandro Salustri

  • 1Department of Cardiology, Second University of Naples, Naples. giodisal@yahoo.it

Clinical Cardiology
|July 28, 2011
PubMed

Insights

Tissue Doppler imaging detects early left ventricular dysfunction in asymptomatic individuals with cardiovascular risk factors. This method offers significant prognostic value beyond identifying risk factors alone, aiding early intervention.

Area of Science:

  • Cardiology
  • Diagnostic Imaging
  • Preventive Medicine

Background:

  • Early detection of left ventricular (LV) dysfunction is crucial in asymptomatic individuals with cardiovascular (CV) risk factors.
  • Tissue Doppler imaging (TDI) is a valuable tool for assessing cardiac function.

Purpose of the Study:

  • To assess the prognostic capability of TDI in identifying early longitudinal ventricular dysfunction.
  • To evaluate TDI's effectiveness in asymptomatic subjects with normal LV systolic and diastolic function but CV risk factors.

Main Methods:

  • A study population of 554 subjects was divided into controls and groups based on the number of CV risk factors (RsF).
  • All subjects underwent standard echo-Doppler evaluation, including posterior wall TDI.
  • Follow-up data were collected over a mean period of 28 months.

Main Results:

  • Eighteen individuals (3.2%) experienced a CV event during follow-up.
  • A peak systolic velocity <7.5 cm/second detected by TDI significantly predicted CV events.
  • TDI findings provided additional predictive value beyond the mere presence of CV risk factors.

Conclusions:

  • TDI can identify subclinical longitudinal LV systolic abnormalities.
  • TDI offers significant prognostic value in asymptomatic individuals with CV risk factors.
  • These findings support TDI's clinical utility for early, personalized preventive strategies in high-risk patients.
Abstract

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