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A Patient-Derived Xenograft Model for Venous Malformation

A Patient-Derived Xenograft Model for Venous Malformation

Published on: June 15, 2020

Multiple cutaneous angiomyxomas in a child.

Nuria Martí¹, Esperanza Jordá, Carlos Monteagudo

¹Department of Dermatology, Hospital Clínico Universitario, Valencia, Spain. nuriamarfa@hotmail.com

Pediatric Dermatology

|July 29, 2011

Summary

Disseminated cutaneous angiomyxomas, rare benign tumors, can occur without Carney complex. This case highlights a unique presentation in an 11-year-old boy with widespread lesions since age two.

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Area of Science:

Dermatology
Pathology
Oncology

Background:

Cutaneous myxomas are rare, benign connective tissue tumors.
Also known as angiomyxomas due to their vascularity.
These lesions are recognized as a component of Carney complex.

Observation:

An 11-year-old boy presented with disseminated cutaneous angiomyxomas.
The lesions first appeared at the age of two.
The patient did not exhibit any other features of Carney complex.

Findings:

The case presents a unique occurrence of widespread cutaneous angiomyxomas.
This presentation is notable for the absence of other Carney complex manifestations.
Histologically, these tumors are characterized by stellate cells in a mucoid stroma.

Implications:

This case expands the understanding of cutaneous angiomyxoma presentations.
It suggests that Carney complex is not a prerequisite for disseminated angiomyxomas.
Further research may clarify the specific etiology and management of isolated disseminated cutaneous angiomyxomas.