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Related Concept Videos

Teeth01:15

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
Overview of Regeneration and Repair01:19

Overview of Regeneration and Repair

Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...

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Related Experiment Video

Updated: May 30, 2026

Guided Endodontics: Three-Dimensional Planning and Template-Aided Preparation of Endodontic Access Cavities
07:14

Guided Endodontics: Three-Dimensional Planning and Template-Aided Preparation of Endodontic Access Cavities

Published on: May 24, 2022

Recommendations for using regenerative endodontic procedures in permanent immature traumatized teeth.

Franklin Garcia-Godoy1, Peter E Murray

  • 1Bioscience Research Center College of Dentistry, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA.

Dental Traumatology : Official Publication of International Association for Dental Traumatology
|July 29, 2011
PubMed
Summary

Regenerative endodontic procedures offer a promising alternative to traditional treatments for immature permanent teeth damaged by trauma. These techniques aim to restore tooth vitality and reduce the risk of tooth loss.

Related Experiment Videos

Last Updated: May 30, 2026

Guided Endodontics: Three-Dimensional Planning and Template-Aided Preparation of Endodontic Access Cavities
07:14

Guided Endodontics: Three-Dimensional Planning and Template-Aided Preparation of Endodontic Access Cavities

Published on: May 24, 2022

Area of Science:

  • Dentistry
  • Regenerative Medicine
  • Endodontics

Background:

  • Traumatic dental injuries frequently affect immature permanent teeth, leading to potential fracture and loss.
  • Regenerative endodontic procedures (REPs) like revascularization, partial pulpotomy, and apexogenesis show promise as alternatives to apexification.
  • Current REPs aim to maintain or restore tooth vitality by disinfecting necrotic tissues and utilizing host cells for regeneration.

Purpose of the Study:

  • To review recent literature on regenerative endodontic procedures for traumatized immature permanent teeth.
  • To propose guidelines for selecting appropriate regenerative or conventional endodontic treatments.
  • To provide recommendations based on various clinical factors like injury type, infection, and tooth development.

Main Methods:

  • Literature review of recent studies on regenerative endodontic procedures.
  • Analysis of case reports and clinical evidence supporting REPs.
  • Development of treatment selection criteria based on clinical parameters.

Main Results:

  • Regenerative endodontic procedures have a good prognosis in several case reports.
  • No standardized treatment protocols currently exist for endodontic regeneration.
  • Long-term evidence for REPs in traumatized teeth with open apices is limited.

Conclusions:

  • Regenerative endodontic procedures can be a viable option for immature traumatized teeth.
  • Careful patient and injury assessment is crucial for successful regenerative outcomes.
  • Revascularization should be considered when conventional treatments are unsuitable or have a poor prognosis.