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Updated: May 30, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
[Microscopic polyangiitis in a patient with systemic sclerosis]
J Duruelo1, E Cuende, E Preciado
1Unidad de Reumatología. Hospital de Txagorritxu. Vitoria. Álava. España.
Abstract:
The coexistence of systemic sclerosis (SSc) and vasculitis has been infrequently reported. We present a 65-year-old man who, 6 years previously, had been diagnosed with limited SSc, and who developed a focal segmental necrotizing crescent glomerulonephritis associated with perinuclear antineutrophil cytoplasmic antibodies with antimyeloperoxidase specificity in the absence of Dpenicillamine exposure.
Insights
Systemic sclerosis (SSc) rarely coexists with vasculitis. This case highlights a patient with limited SSc who developed ANCA-associated glomerulonephritis, specifically antimyeloperoxidase-positive vasculitis, without D-penicillamine use.
Area of Science:
- Nephrology
- Rheumatology
- Immunology
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