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Updated: May 30, 2026

Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons
Published on: January 7, 2019
[Charcot's neuroarthropathy]
C Aguilera-Cros1, J Povedano-Gómez, A García-López
1Sección de Reumatología. Hospital Universitario Virgen del Rocío. Sevilla. España.
Abstract:
Diabetes is the most common cause of neuropathic arthropathy. The most frequent localization is the tarsus. In clinical practice, the insidious painful onset and discrete inflammatory signs of this disease often lead to a mistaken interpretation by the physicians who usually manage these patients (endocrinologists, rheumatologists, podiatrists, etc.), delaying diagnosis with devastating consequences. We report four cases of neuropathic arthropathy in diabetic patients diagnosed in our service. The clinical features that may suggest a diagnosis in the early stages of this entity are stressed.
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Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
