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Updated: May 30, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
[Hormone therapy, fertility and pregnancy in antiphospholipid syndrome]
N Fernández-Llanio1, J J Alegre-Sancho, C Chalmeta-Verdejo
1Sección de Reumatología. Hospital Universitario Dr. Peset. Valencia. España.
Abstract:
Antiphospholipid syndrome (APS) carries a risk of thrombosis and infertility. Consequently the use of any type of hormone therapy and pregnancy in APS requires special considerations. The present article provides a broad review of all these issues. The use of contraception, hormone replacement therapy and selective estrogen receptor modulators in APS are described. In vitro fertilization/embryo transfer and ovarian induction in these patients are reviewed. Lastly, the possible fetal and maternal complications that can occur during pregnancy are described and, based on the literature, recommendations for the management of pregnancy in women with APS are provided.
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