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[Systemic lupus erythematosus. Infrequent clinical aspects].
1Servicio de Enfermedades Sistémicas Autoinmunes/Reumatología. Hospital Universitario Príncipe de Asturias. Departamento de Medicina. Universidad de Alcalá. Alcalá de Henares. Madrid. España.
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with varied symptoms affecting any organ. This review covers unique clinical presentations, including hemophagocytic syndrome and posterior reversible encephalopathy syndrome in SLE patients.
Area of Science:
- Rheumatology
- Immunology
- Internal Medicine
Context:
- Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder.
- SLE exhibits significant heterogeneity in clinical manifestations and immunological profiles.
- The disease can impact virtually any organ system throughout its course.
Purpose:
- To review the diverse clinical presentations of SLE.
- To highlight specific SLE-associated conditions, including hemophagocytic syndrome.
- To discuss recent clinical findings such as posterior reversible encephalopathy syndrome in SLE.
Summary:
- SLE is characterized by broad variability in how it presents clinically and affects the immune system.
- While commonly affecting individuals in their second and third decades, SLE can manifest at any age with distinct features.
- The review focuses on notable clinical scenarios and emerging aspects of SLE.
Impact:
- Enhances understanding of SLE's multifaceted nature.
- Provides insights into rare but significant SLE complications.
- Aids clinicians in recognizing and managing diverse SLE presentations.
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