[Systemic lupus erythematosus. Infrequent clinical aspects]

The SLE is a systemic autoimmune disease that presents a tremendous variability regarding its clinical presentation and immunologic expression. This disease can affect any organ, both as clinical onset or during the course of the disease. People in their second and third decade are most frequently affected, but the illness can debut at any age, with some different clinical peculiarities. SLE-associated clinical situations like hemophagocytic syndrome and some recently published clinical aspects like posterior reversible encephalopathy syndrome are reviewed here.