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Updated: May 30, 2026

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
Published on: March 1, 2024
[Frequency of systemic manifestations in patients with primary Sjögren's syndrome in Argentina]
Federico Zazzetti1, Mariano Adolfo Rivero, Damián Elvio Duartes Noé
1Servicio de Reumatología, Buenos Aires, Argentina. reumatologia@hbritanico.com.ar
Unlabelled:
Twenty to 71% of patients with Sjögren's syndrome (SS) will develop systemic manifestations.
Objective:
To characterize the clinical-serological presentation and the frequency of systemic manifestations in patients with primary SS.
Methods:
Retrospective study including patients with SS visited in "Hospital Británico de Buenos Aires" during the period from January 2000 to August 2008.
Results:
Forty-one patients fulfilled the 2002 American-European classification criteria for SS. All patients were women. Mean age at enrollment was 57.85 ± 12.42 years (range 26-79). Mean duration of the disease was 9.28 years (range 0.08-24). Thirty-three (80.49%) developed systemic manifestations. The most frequent were arthritis, cutaneous vasculitis and polyneuropathy. This group featured more frequently ANA titles ≥ 1/640 and hypocomplementemia; although no statistical significance was found. The frequency of systemic manifestations found was greater than reported in the literature.
Conclusions:
A multidisciplinary approach focusing also on systemic manifestations should be the new standard for management of SS.
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