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Updated: May 30, 2026

Automated Joint Space Detection Improves Bone Segmentation Accuracy
Published on: November 28, 2025
[Biomarkers in rheumatoid arthritis]
Raimon Sanmartí1, José A Gómez-Puerta
1Unidad de Artritis, Servicio de Reumatología, Hospital Clínic de Barcelona, Barcelona, España. sanmarti@clinic.ub.es
Abstract:
The search for biomarkers in rheumatoid arthritis (RA) has been the object of interesting research in the past few years, although results have not always been relevant. Several biomarkers, from several different locations (blood, urine, synovial fluid, synovial tissue) and of different nature (autoantibodies, genetic markers, joint remodeling markers), and related to different outcomes, diagnostic and prognostic markers (joint destruction, disability, lack of remission, mortality, response to anti-rheumatic treatment, etc.) have been studied. The present article reviews research only on soluble biomarkers, mainly those in serum, related to the diagnosis and joint destruction in RA.
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