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Published on: September 20, 2018
Chromoblastomycosis caused by Cladophialophora carrionii in a child from India
Narayanappa Shiroorkar Pradeepkumar1, Noyal Mariya Joseph
1Department of Pathology, Mahatma Gandhi Medical College and Research Institute, Pondicherry, India. dr.pradeep_kumar@yahoo.com
Abstract:
Chromoblastomycosis is a chronic fungal infection of the skin and subcutaneous tissue. It usually occurs following trauma with vegetative matter and mainly affects middle-aged male agricultural workers. Only a few cases have been reported in children. The lesions commonly involve the lower limbs, while the upper limbs and face are only rarely affected. We report a case of cutaneous chromoblastomycosis of the left arm, caused by Cladophialophora carrionii, in a 9-year-old boy from India, who was earlier misdiagnosed as cutaneous tuberculosis. The patient showed a good response to treatment with itraconazole and terbinafine.
Insights
Chromoblastomycosis, a chronic fungal skin infection, is rare in children. This case highlights a successful treatment of a 9-year-old boy with Cladophialophora carrionii using antifungal medications.
Area of Science:
- Mycology
- Dermatology
- Infectious Diseases
Background:
- Chromoblastomycosis is a chronic fungal infection affecting skin and subcutaneous tissue, typically seen in adult males after trauma.
- Lesions commonly occur on lower limbs; upper limb and facial involvement are rare.
- Pediatric cases of chromoblastomycosis are exceptionally infrequent.
Observation:
- A 9-year-old boy from India presented with a rare case of cutaneous chromoblastomycosis on his left arm.
- The initial presentation was misdiagnosed as cutaneous tuberculosis.
- The causative agent was identified as Cladophialophora carrionii.
Findings:
- The patient received treatment with a combination of itraconazole and terbinafine.
- The cutaneous chromoblastomycosis showed a positive response to the prescribed antifungal therapy.
- This case expands the understanding of chromoblastomycosis presentation and treatment in pediatric populations.
Implications:
- This case underscores the importance of considering chromoblastomycosis in pediatric differential diagnoses, even with atypical lesion locations.
- Successful treatment with itraconazole and terbinafine suggests these antifungals are effective in pediatric chromoblastomycosis.
- Highlights the need for accurate diagnosis to ensure timely and appropriate management of this fungal infection in children.
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