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Oral immunotherapy in paraplegic patients with chronic urinary tract infections: a double-blind, placebo-controlled
1Spinal Cord Injury Centre, Geneva University Hospital, Switzerland.
The Journal of Urology
|April 1, 1990
Abstract:
In a 6-month, double-blind, placebo-controlled clinical trial with cross-over, we investigated the efficacy and tolerance of an orally administered bacterial extract in 70 spinal cord injury patients with chronic lower urinary tract infections. In the treated patients, compared to those given placebo, there was a statistically significant decrease in the degree of bacteriuria, a considerably decreased incidence of infectious episodes and a lesser requirement for antibiotics.